Mouse Monoclonal Antibody to MCP-1

Item#:

sAP-0014

Size	Price	Quantity
50.0 ug	$320.00

Catalog Number	sAP-0014
Product Name	Mouse Monoclonal Antibody to MCP-1
Target Molecle	MCP-1
Aliases	MCP1
Species	human
MW	N/A
Enterez GeneID	6347
General Information	Monocyte chemoattractant protein-1 (MCP-1) is a member of the chemokine-beta family of cytokines. The protein is structurally related to the CXC subfamily of cytokines. Members of this subfamily are characterized by two cysteines separated by a single amino acid. This cytokine displays chemotactic activity for monocytes and basophils but not for neutrophils or eosinophils. It has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis and atherosclerosis. It binds to chemokine receptors CCR2 and CCR4. It may play a inprotant role in the initiation and/or progression of pulmonary hypertension (PH). Blockade of a systemic MCP-1 signal pathway in vivo may prevent PH.
Immunogen	Purified recombinant fragment of human MCP-1 expressed in E. Coli.
Clone	MM1A7B8;
Isotype	Mouse IgG1.kappa
Size and Concentration	100µg/1mg/ml
Supplied As	Lyophilized Powder from 100µl of Purified antibody in PBS containing 0.03% sodium azide.
Reconstitution and Storage	Reconstitued with 100µl sterile DI H2O, at stored at 4°C or -20°C for short or long term storage.
Applications	ELISA
References	1. Baggiolini M. et al. 1991. FEBS Lett. 307