Mouse Monoclonal Antibody to IFN-gamma

Item#:

sAP-0009

Size	Price	Quantity
50.0 ug	$320.00

Catalog Number	sAP-0009
Product Name	Mouse Monoclonal Antibody to IFN-gamma
Target Molecle	IFN-gamma
Aliases	IFG; IFI
Species	Human;
MW	19.3kDa
Enterez GeneID	3458
General Information	Interferon-? (IFN-?) is a pro-inflammatory cytokine that is central in host resistance to infection. It is mainly produced by natural killer cells and CD4+ and CD8+ T cells, its receptors are found on nearly all cells, where it activates diverse responses that enable potential host cells to prevent invasive infection by bacteria, parasites and viruses. Takayanagi et al. (2000) demonstrated that IFN-? strongly suppresses osteoclastogenesis by interfering with the RANKL (602642)-RANK (603499) signaling pathway. Tsubota et al. (1999) reported that this upregulation in Sjogren syndrome patients may be controlled by interferon-gamma through the activation of transcription factor NFKB
Immunogen	Purified recombinant fragment of human IFN-? expressed in E. Coli.
Clone	MM3F1E3;
Isotype	Mouse IgG1
Size and Concentration	100µg/1mg/ml
Supplied As	Lyophilized Powder from 100µl of Purified antibody in PBS containing 0.03% sodium azide.
Reconstitution and Storage	Reconstitued with 100µl sterile DI H2O, at stored at 4°C or -20°C for short or long term storage.
Applications	ELISA
References	1. Veillette, A. et al. 1988. Cell 55