Mouse Monoclonal Antibody to Apoa5 (ab)

Item#:

sAP-0006

Size	Price	Quantity
50.0 ug	$320.00

Catalog Number	sAP-0006
Product Name	Mouse Monoclonal Antibody to Apoa5 (ab)
Target Molecle	Apoa5 (ab)
Aliases	RAP3; APOAV; APOA-V
Species	Human;
MW	N/A
Enterez GeneID	116519
General Information	Apolipoprotein A5 (ApoA5) is fast gaining attention as a key regulator of serum triglyceride concentrations. An ApoA5 mouse knock-out model produced an approximately four fold increase in serum triglycerides, whereas a knock-in model with human ApoA5 produced 50¿70% lower ; concentrations of mouse serum triglycerides. In addition, peroxisome proliferator-activated receptor-_ agonists, which are used clinically to lower serum triglyceride concentrations, cause increased ApoA5 mRNA expression. Recently, it was demonstrated that ApoA5 is present in human serum detected by polyclonal antibodies against both the NH2 and COOH termini, although at much lower concentration than other apolipoproteins.
Immunogen	Purified recombinant fragment of human APOA5 (AA
Clone	MM1G5G9(c);
Isotype	Mouse IgG1
Size and Concentration	100µg/1mg/ml
Supplied As	Lyophilized Powder from 100µl of Purified antibody in PBS containing 0.03% sodium azide.
Reconstitution and Storage	Reconstitued with 100µl sterile DI H2O, at stored at 4°C or -20°C for short or long term storage.
Applications	ELISA
References	1. Pennacchio, L. et al. Science 2001 294, 169-173. ; 2. Prieur, X. et al. (2003) J Biol Chem 278, 25468-25480. ; 3. Obrien, PJ. et al. (2005) Clin Chem 51