Goat anti-TDP1 Antibody |
| Principle Name | TDP1 |
| Official Symbol | TDP1 |
| All Name and Symbols | TDP1; tyrosyl-DNA phosphodiesterase 1; FLJ11090; MGC104252 |
| Accession Number(s) | NP_060789.2 |
| Peptide Sequence | PNDGTAQRTENHG, is from internal region |
| Human Gene ID(s) | 55775 |
| Non-Human GeneID(s) | |
| Important Comments | Reported variants represent identical protein |
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Supplied As | lyophilized powder of 50ug or 100ug IgG; Reconsititute IgG with 100ul or 200ul sterile DI Water and final product will be formulated as 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Aliquot and store at -20°C. Minimize freezing and thawing. |
| Applications | Pep ELISA, WB |
| Tested Species | Human |
| Peptide ELISA | antibody detection limit dilution 1 to 8000. |
| Western Blot | Approx 75kDa band observed in nuclear lysates of cell line Jurkat (calculated MW of 68.4kDa according to NP_060789.2). Recommended concentration |
| Reference(s) | Antony S, Marchand C, Stephen AG, Thibaut L, Agama KK, Fisher RJ, Pommier Y Novel high-throughput electrochemiluminescent assay for identification of human tyrosyl-DNA phosphodiesterase (Tdp1) inhibitors and characterization of furamidine (NSC 305831) as an inhibitor of Tdp1 Nucleic Acids Res. 2007;35(13) |
