Goat anti-NTRK2 Antibody |
| Principle Name | NTRK2 |
| Official Symbol | NTRK2 |
| All Name and Symbols | NTRK2; neurotrophic tyrosine kinase, receptor, type 2; GP145-TrkB; TRKB ; BDNF/NT-3 growth factors receptor; tyrosine kinase receptor B; BDNF receptor |
| Accession Number(s) | NP_006171.2; NP_001007098.1; NP_001018074.1; NP_001018075.1; NP_001018076.1 |
| Peptide Sequence | KTLQEAKSSPDTQ, is from internal region |
| Human Gene ID(s) | 4915 |
| Non-Human GeneID(s) | |
| Important Comments | This antibody is expected to recognise isoforms a (NP_006171.2), b ((NP_001007098.1), c (NP_001018074.1), d (NP_001018075.1), e ( NP_001018076.1). |
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Supplied As | lyophilized powder of 50ug or 100ug IgG; Reconsititute IgG with 100ul or 200ul sterile DI Water and final product will be formulated as 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Aliquot and store at -20°C. Minimize freezing and thawing. |
| Applications | Pep ELISA, WB |
| Tested Species | Human |
| Peptide ELISA | antibody detection limit dilution 1 to 64000. |
| Western Blot | Approx 100kDa band observed in Human Brain (Hippocampus, Cerebral Cortex and Cerebellum) lysates (calculated MW of 93.8kDa according to NP_006171.2). Recommended concentration |
| Reference(s) | Hashimoto T, Bergen SE, Nguyen QL, Xu B, Monteggia LM, Pierri JN, Sun Z, Sampson AR, Lewis DA. Relationship of brain-derived neurotrophic factor and its receptor TrkB to altered inhibitory prefrontal circuitry in schizophrenia. J Neurosci. 2005 Jan 12;25(2) |
