Home Page > ANTIBODY > POLYCLONAL ANTIBODY > Goat Polyclonal Antibodies >  Goat anti-MK2 / MAPKAPK2 Antibody

Goat anti-MK2 / MAPKAPK2 Antibody
Item#:
dAP-2869
Size Price Quantity
50.0 ug $310.00
Goat anti-MK2 / MAPKAPK2 Antibody
Principle Name MK2 / MAPKAPK2
Official Symbol MAPKAPK2
All Name and Symbols MAPKAPK2; mitogen-activated protein kinase-activated protein kinase 2; MAPKAP-K2; MK-2; MK2; MAP kinase-activated protein kinase 2; MAPK-activated protein kinase 2; MAPKAP kinase 2
Accession Number(s) NP_004750.1; NP_116584.2
Peptide Sequence SRVLKEDKERWED, is from internal region (near C Terminus)
Human Gene ID(s) 9261
Non-Human GeneID(s) 17164 (mouse); 289014 (rat);
Important Comments This antibody is expected to recognize both reported isoforms (NP_004750.1; NP_116584.2).
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Supplied As lyophilized powder of 50ug or 100ug IgG; Reconsititute IgG with 100ul or 200ul sterile DI Water and final product will be formulated as 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.
Applications Pep ELISA, WB, IP
Tested Species Mouse
Peptide ELISA antibody detection limit dilution 1 to 128000.
Western Blot Approx 60kDa band observed in Mouse Embryonic Fibroblasts (MEF) lysates, not present in the knockout MEFs and reappearing as a 45kDa band upon reintroduction of MK2 gene expression through viral transduction (calculated MW of 44.0kDa accord
Reference(s) Yang Y, Xia F, Hermance N, Mabb A, Simonson S, Morrissey S, Gandhi P, Munson M, Miyamoto S, Kelliher MA. A cytosolic ATM/NEMO/RIP1 complex recruits TAK1 to mediate the NF-kappaB and p38 mitogen-activated protein kinase (MAPK)/MAPK-activated protein 2 responses to DNA damage. Mol Cell Biol. 2011 Jul;31(14)

ANGIO-PROTEOMIE, ALL RIGHTS RESERVED