Goat anti-KCNN2 Antibody |
| Principle Name | KCNN2 |
| Official Symbol | KCNN2 |
| All Name and Symbols | KCNN2; potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2; KCa2.2; SK2; SKCA2; hSK2; apamin-sensitive small-conductance Ca2+-activated potassium channel; small conductance calcium-activated potassium channel protein |
| Accession Number(s) | NP_067627.2; NP_740721.1 |
| Peptide Sequence | ESYDKHVTYNAER, is from internal region |
| Human Gene ID(s) | 3781 |
| Non-Human GeneID(s) | 140492 (mouse); 54262 (rat); |
| Important Comments | This antibody is expected to recognize both isoforms (NP_067627.2; NP_740721.1). |
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Supplied As | lyophilized powder of 50ug or 100ug IgG; Reconsititute IgG with 100ul or 200ul sterile DI Water and final product will be formulated as 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Aliquot and store at -20°C. Minimize freezing and thawing. |
| Applications | Pep ELISA, WB, IHC |
| Tested Species | Human |
| Peptide ELISA | antibody detection limit dilution 1 to 64000. |
| Western Blot | Approx 70kDa and 23kDa bands observed in Human Liver lysates (calculated MW of 63.8kDa according to NP_067627.2 and of 26.3kDa according to NP_740721.1). Recommended concentration |
| Immunohistochemistry | In paraffin embedded Humam Thyroid Gland shows membranous staining in the epithelial cells. Recommended concentration, 1-2µg/ml. |
| Reference(s) | Morimoto T, Ohya S, Hayashi H, Onozaki K, Imaizumi Y, Cell-cycle-dependent regulation of Ca2+-activated K+ channel in Jurkat T-lymphocyte. Journal of pharmacological sciences 2007 May 104 (1) |
