Goat anti-SNX1 Antibody |
| Principle Name | SNX1 |
| Official Symbol | SNX1 |
| All Name and Symbols | SNX1; sorting nexin 1; HsT17379; MGC8664; SNX1A; Vps5; sorting nexin 1A |
| Accession Number(s) | NP_003090.2; NP_690039.1 |
| Peptide Sequence | TNSSKPQPTYEELE, is from internal region |
| Human Gene ID(s) | 6642 |
| Non-Human GeneID(s) | 56440 (mouse); 84471 (rat); |
| Important Comments | This antibody is expected to recognize isoform a and c (NP_003090.2; NP_690039.1. |
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Supplied As | lyophilized powder of 50ug or 100ug IgG; Reconsititute IgG with 100ul or 200ul sterile DI Water and final product will be formulated as 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Aliquot and store at -20°C. Minimize freezing and thawing. |
| Applications | Pep ELISA, WB, IHC, ICC |
| Tested Species | Human |
| Peptide ELISA | antibody detection limit dilution 1 to 64000. |
| Western Blot | Approx 75kDa band observed in Human lysates of cell line HeLa (calculated MW of 59.1kDa according to NP_003090.2). The observed molecular weight corresponds to earlier findings with different antibodies from other commercial sources. Recomm |
| Immunohistochemistry | In paraffin embedded Human Uterus shows vesicular staining in the cytoplasm of endometrial epithelium. Recommended concentration, 3-5µg/ml. |
| Reference(s) | Mari M, Bujny MV, Zeuschner D, Geerts WJ, Griffith J, Petersen CM, Cullen PJ, Klumperman J, Geuze HJ, SNX1 defines an early endosomal recycling exit for sortilin and mannose 6-phosphate receptors. Traffic (Copenhagen, Denmark) 2008 Mar 9 (3) |
