Goat anti-PDE11A Antibody |
| Principle Name | PDE11A |
| Official Symbol | PDE11A |
| All Name and Symbols | PDE11A; phosphodiesterase 11A ; FLJ23693; MGC133355; MGC133356; PPNAD2 ; cAMP and cGMP cyclic nucleotide phosphodiesterase 11A; cyclic nucleotide phosphodiesterase 11A; dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A |
| Accession Number(s) | NP_058649.3 ; NP_001070665.1; NP_001070826.1; NP_001070664.1 |
| Peptide Sequence | NSFKESMEKSSYSD, is from internal region |
| Human Gene ID(s) | 50940 |
| Non-Human GeneID(s) | 241489 (mouse); 140928 (rat); |
| Important Comments | This antibody is expected to recognise all four reported isoforms (NP_058649.3 ; NP_001070665.1; NP_001070826.1; NP_001070664.1). |
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Supplied As | lyophilized powder of 50ug or 100ug IgG; Reconsititute IgG with 100ul or 200ul sterile DI Water and final product will be formulated as 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Aliquot and store at -20°C. Minimize freezing and thawing. |
| Applications | Pep ELISA, WB, IHC |
| Tested Species | Human |
| Peptide ELISA | antibody detection limit dilution 1 to 2000. |
| Western Blot | Approx 60-65kDa band observed in Human Skeletal Muscle and Human Prostate lysates (calculated MW of 65.7kDa according to NP_001070826.1). Recommended concentration |
| Immunohistochemistry | Paraffin embedded Human Prostate. Recommended concentration |
| Reference(s) | Horvath A, Boikos S, Giatzakis C, Robinson-White A, Groussin L, Griffin KJ, Stein E, Levine E, Delimpasi G, Hsiao HP, Keil M, Heyerdahl S, Matyakhina L, Libe R, Fratticci A, Kirschner LS, Cramer K, Gaillard RC, Bertagna X, Carney JA, Bertherat J, Bossis I A genome-wide scan identifies mutations in the gene encoding phosphodiesterase 11A4 (PDE11A) in individuals with adrenocortical hyperplasia. Nat Genet. 2006 Jul;38(7) |
