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Goat anti-Proopiomelanocortin / POMC Antibody
Item#:
dAP-0645
Size Price Quantity
50.0 ug $310.00
Goat anti-Proopiomelanocortin / POMC Antibody
Principle Name Proopiomelanocortin / POMC
Official Symbol POMC
All Name and Symbols POMC; proopiomelanocortin; Precursor of MSH, POC, ACTH, CLIP, adrenocorticotropin/ beta-lipotropin/ alpha-melanocyte stimulating hormone/ beta-melanocyte stimulating; hormone/ beta-endorphin; LPH; NPP; OTTHUMP00000119991; OTTHUMP00000200964; adrenocortic
Accession Number(s) NP_000930.1; NP_001030333.1
Peptide Sequence NAIIKNAYKKGE, is from C Terminus
Human Gene ID(s) 5443
Non-Human GeneID(s)
Important Comments Both transcript variants encode the same protein. In Western blot, this product appears to react with the full length precursor protein only.
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Supplied As lyophilized powder of 50ug or 100ug IgG; Reconsititute IgG with 100ul or 200ul sterile DI Water and final product will be formulated as 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.
Applications Pep ELISA, WB, IHC
Tested Species Human, Mouse
Peptide ELISA antibody detection limit dilution 1 to 128000.
Western Blot Approx 29kDa band observed in lysates of cell line NIH3T3 (calculated MW of 29.4kDa according to NP_000930.1 and NP_001030333.1). Recommended concentration
Immunohistochemistry In paraffin embedded Human Anterior Pituitary Gland shows vesilulate staining in glandular cells. Recommended concentration
Reference(s) Muhlhausler BS, Adam CL, Marrocco E, Findlay PA, Roberts CT, McFarlane JR, Kauter KG, McMillen IC. Impact of glucose infusion on the structural and functional characteristics of adipose tissue and on hypothalamic gene expression for appetite regulatory neuropeptides in the sheep fetus during late gestation. J Physiol. 2005 Jan 20; [Epub ahead of print] .PMID

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