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Mouse Monoclonal Antibody to GRM8


Item#:
sAP-1747
Size Price Quantity
100.0 ug $341.00
Catalog Number sAP-1747
Product Name Mouse Monoclonal Antibody to GRM8
Target Molecle GRM8
Aliases GLUR8; mGlu8; GPRC1H; MGLUR8
Species Human;
MW 101.7kDa
Enterez GeneID 2918
General Information L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Immunogen Purified recombinant fragment of human GRM8 (AA
Clone MM4C1C1
Isotype Mouse IgG1
Size and Concentration 100µg/1mg/ml
Supplied As Lyophilized Powder from 100µl of Purified antibody in PBS with 0.05% sodium azide
Reconstitution and Storage Reconstitued with 100µl sterile DI H2O, at stored at 4°C or -20°C for short or long term storage.
Applications ELISA
References 1.Biol Blood Marrow Transplant. 2015 Mar;21(3)

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