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Mouse Monoclonal Antibody to CD268


Item#:
sAP-1744
Size Price Quantity
100.0 ug $341.00
Catalog Number sAP-1744
Product Name Mouse Monoclonal Antibody to CD268
Target Molecle CD268
Aliases TNFRSF13C; BAFFR; CVID4; BAFF-R; BROMIX; prolixin
Species Human;
MW 18.9kDa
Enterez GeneID 115650
General Information B cell-activating factor (BAFF) enhances B-cell survival in vitro and is a regulator of the peripheral B-cell population. Overexpression of Baff in mice results in mature B-cell hyperplasia and symptoms of systemic lupus erythematosus (SLE). Also, some SLE patients have increased levels of BAFF in serum. Therefore, it has been proposed that abnormally high levels of BAFF may contribute to the pathogenesis of autoimmune diseases by enhancing the survival of autoreactive B cells. The protein encoded by this gene is a receptor for BAFF and is a type III transmembrane protein containing a single extracellular cysteine-rich domain. It is thought that this receptor is the principal receptor required for BAFF-mediated mature B-cell survival.
Immunogen Purified recombinant fragment of human CD268 (AA
Clone MM5A9B10
Isotype Mouse IgG2b
Size and Concentration 100µg/1mg/ml
Supplied As Lyophilized Powder from 100µl of Purified antibody in PBS with 0.05% sodium azide
Reconstitution and Storage Reconstitued with 100µl sterile DI H2O, at stored at 4°C or -20°C for short or long term storage.
Applications ELISA
References 1.Oncol Rep. 2015 Aug;34(2)

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