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Mouse Monoclonal Antibody to APAF1


Item#:
sAP-1731
Size Price Quantity
100.0 ug $341.00
Catalog Number sAP-1731
Product Name Mouse Monoclonal Antibody to APAF1
Target Molecle APAF1
Aliases CED4; APAF-1
Species Human;
MW 141.8kDa
Enterez GeneID 317
General Information This gene encodes a cytoplasmic protein that initiates apoptosis. This protein contains several copies of the WD-40 domain, a caspase recruitment domain (CARD), and an ATPase domain (NB-ARC). Upon binding cytochrome c and dATP, this protein forms an oligomeric apoptosome. The apoptosome binds and cleaves caspase 9 preproprotein, releasing its mature, activated form. Activated caspase 9 stimulates the subsequent caspase cascade that commits the cell to apoptosis. Alternative splicing results in several transcript variants encoding different isoforms.
Immunogen Purified recombinant fragment of human APAF1 (AA
Clone MM2H9G5
Isotype Mouse IgG2b
Size and Concentration 100µg/1mg/ml
Supplied As Lyophilized Powder from 100µl of Purified antibody in PBS with 0.05% sodium azide
Reconstitution and Storage Reconstitued with 100µl sterile DI H2O, at stored at 4°C or -20°C for short or long term storage.
Applications ELISA
References 1.Oncol Rep. 2014 Oct;32(4)

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