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Mouse Monoclonal Antibody to CD172A


Item#:
sAP-1707
Size Price Quantity
100.0 ug $341.00
Catalog Number sAP-1707
Product Name Mouse Monoclonal Antibody to CD172A
Target Molecle CD172A
Aliases BIT; MFR; P84; SIRP; MYD-1; SHPS1; SIRPA; PTPNS1
Species Human;
MW 55kDa
Enterez GeneID 140885
General Information The protein encoded by this gene is a member of the signal-regulatory-protein (SIRP) family, and also belongs to the immunoglobulin superfamily. SIRP family members are receptor-type transmembrane glycoproteins known to be involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes. This protein can be phosphorylated by tyrosine kinases. The phospho-tyrosine residues of this PTP have been shown to recruit SH2 domain containing tyrosine phosphatases (PTP), and serve as substrates of PTPs. This protein was found to participate in signal transduction mediated by various growth factor receptors. CD47 has been demonstrated to be a ligand for this receptor protein. This gene and its product share very high similarity with several other members of the SIRP family. These related genes are located in close proximity to each other on chromosome 20p13. Multiple alternatively spliced transcript variants have been determined for this gene.
Immunogen Purified recombinant fragment of human CD172A (AA
Clone MM2H7E2
Isotype Mouse IgG1
Size and Concentration 100µg/1mg/ml
Supplied As Lyophilized Powder from 100µl of Purified antibody in PBS with 0.05% sodium azide
Reconstitution and Storage Reconstitued with 100µl sterile DI H2O, at stored at 4°C or -20°C for short or long term storage.
Applications ELISA
References 1.Cancer Res. 2014 Apr 1;74(7)

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