Mouse Monoclonal Antibody to CD152

Item#:

sAP-1683

Size	Price	Quantity
50.0 ug	$245.00
100.0 ug	$320.00

Catalog Number	sAP-1683
Product Name	Mouse Monoclonal Antibody to CD152
Target Molecle	CD152
Aliases	CTLA4; CD; GSE; GRD4; ALPS5; CTLA-4; IDDM12; CELIAC3
Species	Human;
MW	24.6kDa
Enterez GeneID	1493
General Information	This gene is a member of the immunoglobulin superfamily and encodes a protein which transmits an inhibitory signal to T cells. The protein contains a V domain, a transmembrane domain, and a cytoplasmic tail. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. The membrane-bound isoform functions as a homodimer interconnected by a disulfide bond, while the soluble isoform functions as a monomer. Mutations in this gene have been associated with insulin-dependent diabetes mellitus, Graves disease, Hashimoto thyroiditis, celiac disease, systemic lupus erythematosus, thyroid-associated orbitopathy, and other autoimmune diseases.
Immunogen	Purified recombinant fragment of human CD152 (AA
Clone	MM8B3F8
Isotype	Mouse IgG1
Size and Concentration	100µg/1mg/ml
Supplied As	Lyophilized Powder from 100µl of Purified antibody in PBS with 0.05% sodium azide
Reconstitution and Storage	Reconstitued with 100µl sterile DI H2O, at stored at 4°C or -20°C for short or long term storage.
Applications	ELISA
References	1.Int J Clin Exp Pathol. 2013 Apr 15;6(5)