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ANTIBODY
PRIMARY CELL
RECOMBINANT PROTEIN
MOLECULAR BIOLOGY
CUSTOM BASED SERVICE
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> Mouse Monoclonal Antibody to CD152
Mouse Monoclonal Antibody to CD152
Item#:
sAP-1683
Size
Price
Quantity
100.0 ug
$341.00
Product Overview
Data Sheet
Catalog Number
sAP-1683
Product Name
Mouse Monoclonal Antibody to CD152
Target Molecle
CD152
Aliases
CTLA4; CD; GSE; GRD4; ALPS5; CTLA-4; IDDM12; CELIAC3
Species
Human;
MW
24.6kDa
Enterez GeneID
1493
General Information
This gene is a member of the immunoglobulin superfamily and encodes a protein which transmits an inhibitory signal to T cells. The protein contains a V domain, a transmembrane domain, and a cytoplasmic tail. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. The membrane-bound isoform functions as a homodimer interconnected by a disulfide bond, while the soluble isoform functions as a monomer. Mutations in this gene have been associated with insulin-dependent diabetes mellitus, Graves disease, Hashimoto thyroiditis, celiac disease, systemic lupus erythematosus, thyroid-associated orbitopathy, and other autoimmune diseases.
Immunogen
Purified recombinant fragment of human CD152 (AA
Clone
MM8B3F8
Isotype
Mouse IgG1
Size and Concentration
100µg/1mg/ml
Supplied As
Lyophilized Powder from 100µl of Purified antibody in PBS with 0.05% sodium azide
Reconstitution and Storage
Reconstitued with 100µl sterile DI H2O, at stored at 4°C or -20°C for short or long term storage.
Applications
ELISA
References
1.Int J Clin Exp Pathol. 2013 Apr 15;6(5)
sAP-1683 Mouse Monoclonal Antibody to CD152.pdf
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