Home Page > ANTIBODY > Conventional Antibody >  Mouse Monoclonal Antibody to ELANE

Mouse Monoclonal Antibody to ELANE


Item#:
sAP-1662
Size Price Quantity
100.0 ug $341.00
Catalog Number sAP-1662
Product Name Mouse Monoclonal Antibody to ELANE
Target Molecle ELANE
Aliases GE; NE; HLE; HNE; ELA2; SCN1; PMN-E
Species Human;Monkey;
MW 28.5kDa
Enterez GeneID 1991
General Information Elastases form a subfamily of serine proteases that hydrolyze many proteins in addition to elastin. Humans have six elastase genes which encode structurally similar proteins. The encoded preproprotein is proteolytically processed to generate the active protease. Following activation, this protease hydrolyzes proteins within specialized neutrophil lysosomes, called azurophil granules, as well as proteins of the extracellular matrix. The enzyme may play a role in degenerative and inflammatory diseases through proteolysis of collagen-IV and elastin. This protein also degrades the outer membrane protein A (OmpA) of E. coli as well as the virulence factors of such bacteria as Shigella, Salmonella and Yersinia. Mutations in this gene are associated with cyclic neutropenia and severe congenital neutropenia (SCN). This gene is present in a gene cluster on chromosome 19.
Immunogen Purified recombinant fragment of human ELANE (AA
Clone MM6B6B10
Isotype Mouse IgG1
Size and Concentration 100µg/1mg/ml
Supplied As Lyophilized Powder from 100µl of Purified antibody in PBS with 0.05% sodium azide
Reconstitution and Storage Reconstitued with 100µl sterile DI H2O, at stored at 4°C or -20°C for short or long term storage.
Applications ELISA
References 1.J Neural Transm (Vienna). 2014 May;121(5)

ANGIO-PROTEOMIE, ALL RIGHTS RESERVED