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Mouse Monoclonal Antibody to ADORA2A


Item#:
sAP-1630
Size Price Quantity
100.0 ug $341.00
Catalog Number sAP-1630
Product Name Mouse Monoclonal Antibody to ADORA2A
Target Molecle ADORA2A
Aliases A2aR; RDC8; ADORA2
Species Human;
MW 44.7kDa
Enterez GeneID 135
General Information This gene encodes a member of the guanine nucleotide-binding protein (G protein)-coupled receptor (GPCR) superfamily, which is subdivided into classes and subtypes. The receptors are seven-pass transmembrane proteins that respond to extracellular cues and activate intracellular signal transduction pathways. This protein, an adenosine receptor of A2A subtype, uses adenosine as the preferred endogenous agonist and preferentially interacts with the G(s) and G(olf) family of G proteins to increase intracellular cAMP levels. It plays an important role in many biological functions, such as cardiac rhythm and circulation, cerebral and renal blood flow, immune function, pain regulation, and sleep. It has been implicated in pathophysiological conditions such as inflammatory diseases and neurodegenerative disorders. Alternative splicing results in multiple transcript variants. A read-through transcript composed of the upstream SPECC1L (sperm antigen with calponin homology and coiled-coil domains 1-like) and ADORA2A (adenosine A2a receptor) gene sequence has been identified, but it is thought to be non-coding.
Immunogen Purified recombinant fragment of human ADORA2A (AA
Clone MM6A6G11
Isotype Mouse IgG2a
Size and Concentration 100µg/1mg/ml
Supplied As Lyophilized Powder from 100µl of Purified antibody in PBS with 0.05% sodium azide
Reconstitution and Storage Reconstitued with 100µl sterile DI H2O, at stored at 4°C or -20°C for short or long term storage.
Applications ELISA
References 1.Oncotarget. 2014 Aug 30;5(16)

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