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Mouse Monoclonal Antibody to GRM6


Item#:
sAP-1616
Size Price Quantity
100.0 ug $341.00
Catalog Number sAP-1616
Product Name Mouse Monoclonal Antibody to GRM6
Target Molecle GRM6
Aliases mGlu6; CSNB1B; GPRC1F; MGLUR6
Species Human;
MW 95.5kDa
Enterez GeneID 2916
General Information L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities.
Immunogen Purified recombinant fragment of human GRM6 (AA
Clone MM7D9C9
Isotype Mouse IgG1
Size and Concentration 100µg/1mg/ml
Supplied As Lyophilized Powder from 100µl of Purified antibody in PBS with 0.05% sodium azide
Reconstitution and Storage Reconstitued with 100µl sterile DI H2O, at stored at 4°C or -20°C for short or long term storage.
Applications ELISA
References 1.Breast Cancer Res Treat. 2015 May;151(1)

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