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Mouse Monoclonal Antibody to CTNNB1


Item#:
sAP-1609
Size Price Quantity
100.0 ug $341.00
Catalog Number sAP-1609
Product Name Mouse Monoclonal Antibody to CTNNB1
Target Molecle CTNNB1
Aliases CTNNB; MRD19; armadillo
Species Human;
MW 85.5kDa
Enterez GeneID 1499
General Information The protein encoded by this gene is part of a complex of proteins that constitute adherens junctions (AJs). AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. The encoded protein also anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete. Finally, this protein binds to the product of the APC gene, which is mutated in adenomatous polyposis of the colon. Mutations in this gene are a cause of colorectal cancer (CRC), pilomatrixoma (PTR), medulloblastoma (MDB), and ovarian cancer. Alternative splicing results in multiple transcript variants.
Immunogen Purified recombinant fragment of human CTNNB1 (AA
Clone MM7C5D2
Isotype Mouse IgG2b
Size and Concentration 100µg/1mg/ml
Supplied As Lyophilized Powder from 100µl of Purified antibody in PBS with 0.05% sodium azide
Reconstitution and Storage Reconstitued with 100µl sterile DI H2O, at stored at 4°C or -20°C for short or long term storage.
Applications ELISA
References 1.Anticancer Res. 2016 Apr;36(4)

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