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Mouse Monoclonal Antibody to PRKAB2


Item#:
sAP-1607
Size Price Quantity
100.0 ug $341.00
Catalog Number sAP-1607
Product Name Mouse Monoclonal Antibody to PRKAB2
Target Molecle PRKAB2
Aliases
Species Human;
MW 30.3kDa
Enterez GeneID 5565
General Information The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit may be a positive regulator of AMPK activity. It is highly expressed in skeletal muscle and thus may have tissue-specific roles. Multiple alternatively spliced transcript variants have been found for this gene.
Immunogen Purified recombinant fragment of human PRKAB2 (AA
Clone MM8F5B2
Isotype Mouse IgG1
Size and Concentration 100µg/1mg/ml
Supplied As Lyophilized Powder from 100µl of Purified antibody in PBS with 0.05% sodium azide
Reconstitution and Storage Reconstitued with 100µl sterile DI H2O, at stored at 4°C or -20°C for short or long term storage.
Applications ELISA
References 1.Mol Biol Cell. 2013 Jun;24(11)

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