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Mouse Monoclonal Antibody to CHRNA2


Item#:
sAP-1599
Size Price Quantity
100.0 ug $341.00
Catalog Number sAP-1599
Product Name Mouse Monoclonal Antibody to CHRNA2
Target Molecle CHRNA2
Aliases
Species Human;
MW 60kDa
Enterez GeneID 1135
General Information Nicotinic acetylcholine receptors (nAChRs) are ligand-gated ion channels formed by a pentameric arrangement of alpha and beta subunits to create distinct muscle and neuronal receptors. Neuronal receptors are found throughout the peripheral and central nervous system where they are involved in fast synaptic transmission. This gene encodes an alpha subunit that is widely expressed in the brain. The proposed structure for nAChR subunits is a conserved N-terminal extracellular domain followed by three conserved transmembrane domains, a variable cytoplasmic loop, a fourth conserved transmembrane domain, and a short C-terminal extracellular region. Mutations in this gene cause autosomal dominant nocturnal frontal lobe epilepsy type 4. Single nucleotide polymorphisms (SNPs) in this gene have been associated with nicotine dependence.
Immunogen Purified recombinant fragment of human CHRNA2 (AA
Clone MM7G12D10
Isotype Mouse IgG1
Size and Concentration 100µg/1mg/ml
Supplied As Lyophilized Powder from 100µl of Purified antibody in PBS with 0.05% sodium azide
Reconstitution and Storage Reconstitued with 100µl sterile DI H2O, at stored at 4°C or -20°C for short or long term storage.
Applications ELISA
References 1.Hum Genet. 2014 May;133(5)

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