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Mouse Monoclonal Antibody to BCR


Item#:
sAP-1592
Size Price Quantity
100.0 ug $341.00
Catalog Number sAP-1592
Product Name Mouse Monoclonal Antibody to BCR
Target Molecle BCR
Aliases ALL; CML; PHL; BCR1; D22S11; D22S662
Species Human;
MW 142.8kDa
Enterez GeneID 613
General Information A reciprocal translocation between chromosomes 22 and 9 produces the Philadelphia chromosome, which is often found in patients with chronic myelogenous leukemia. The chromosome 22 breakpoint for this translocation is located within the BCR gene. The translocation produces a fusion protein which is encoded by sequence from both BCR and ABL, the gene at the chromosome 9 breakpoint. Although the BCR-ABL fusion protein has been extensively studied, the function of the normal BCR gene product is not clear. The protein has serine/threonine kinase activity and is a GTPase-activating protein for p21rac. Two transcript variants encoding different isoforms have been found for this gene.
Immunogen Purified recombinant fragment of human BCR (AA
Clone MM1E11G12
Isotype Mouse IgG1
Size and Concentration 100µg/1mg/ml
Supplied As Lyophilized Powder from 100µl of Purified antibody in PBS with 0.05% sodium azide
Reconstitution and Storage Reconstitued with 100µl sterile DI H2O, at stored at 4°C or -20°C for short or long term storage.
Applications ELISA
References 1.Curr Alzheimer Res. 2014;11(7)

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