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Mouse Monoclonal Antibody to BAX


Item#:
sAP-1580
Size Price Quantity
100.0 ug $341.00
Catalog Number sAP-1580
Product Name Mouse Monoclonal Antibody to BAX
Target Molecle BAX
Aliases BCL2L4
Species Human;
MW 21.2kDa
Enterez GeneID 581
General Information The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein forms a heterodimer with BCL2, and functions as an apoptotic activator. This protein is reported to interact with, and increase the opening of, the mitochondrial voltage-dependent anion channel (VDAC), which leads to the loss in membrane potential and the release of cytochrome c. The expression of this gene is regulated by the tumor suppressor P53 and has been shown to be involved in P53-mediated apoptosis. Multiple alternatively spliced transcript variants, which encode different isoforms, have been reported for this gene.
Immunogen Purified recombinant fragment of human BAX (AA
Clone MM4H9B11
Isotype Mouse IgG2a
Size and Concentration 100µg/1mg/ml
Supplied As Lyophilized Powder from 100µl of Purified antibody in PBS with 0.05% sodium azide
Reconstitution and Storage Reconstitued with 100µl sterile DI H2O, at stored at 4°C or -20°C for short or long term storage.
Applications ELISA
References 1.J Biol Chem. 2007 Jun 22;282(25)

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