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Mouse Monoclonal Antibody to AXIN1


Item#:
sAP-1546
Size Price Quantity
100.0 ug $341.00
Catalog Number sAP-1546
Product Name Mouse Monoclonal Antibody to AXIN1
Target Molecle AXIN1
Aliases AXIN; PPP1R49
Species Human;
MW 95.6kDa
Enterez GeneID 8312
General Information This gene encodes a cytoplasmic protein which contains a regulation of G-protein signaling (RGS) domain and a dishevelled and axin (DIX) domain. The encoded protein interacts with adenomatosis polyposis coli, catenin beta-1, glycogen synthase kinase 3 beta, protein phosphate 2, and itself. This protein functions as a negative regulator of the wingless-type MMTV integration site family, member 1 (WNT) signaling pathway and can induce apoptosis. The crystal structure of a portion of this protein, alone and in a complex with other proteins, has been resolved. Mutations in this gene have been associated with hepatocellular carcinoma, hepatoblastomas, ovarian endometriod adenocarcinomas, and medullablastomas. Alternative splicing results in multiple transcript variants.
Immunogen Purified recombinant fragment of human 4F10G1 (AA
Clone MM4F10G1
Isotype Mouse IgG1
Size and Concentration 100µg/1mg/ml
Supplied As Lyophilized Powder from 100µl of Purified antibody in PBS with 0.05% sodium azide
Reconstitution and Storage Reconstitued with 100µl sterile DI H2O, at stored at 4°C or -20°C for short or long term storage.
Applications ELISA
References 1.Hum Reprod. 2013 Mar;28(3)

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