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Mouse Monoclonal Antibody to PRKAG3


Item#:
sAP-1520
Size Price Quantity
100.0 ug $341.00
Catalog Number sAP-1520
Product Name Mouse Monoclonal Antibody to PRKAG3
Target Molecle PRKAG3
Aliases AMPKG3
Species Human;
MW 54.3kDa
Enterez GeneID 53632
General Information The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit is one of the gamma regulatory subunits of AMPK. It is dominantly expressed in skeletal muscle. Studies of the pig counterpart suggest that this subunit may play a key role in the regulation of energy metabolism in skeletal muscle.
Immunogen Purified recombinant fragment of human PRKAG3 (AA
Clone MM1C5D10
Isotype Mouse IgG1
Size and Concentration 100µg/1mg/ml
Supplied As Lyophilized Powder from 100µl of Purified antibody in PBS with 0.05% sodium azide
Reconstitution and Storage Reconstitued with 100µl sterile DI H2O, at stored at 4°C or -20°C for short or long term storage.
Applications ELISA
References 1.Diabetologia. 2010 Sep;53(9)

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