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Mouse Monoclonal Antibody to PRKAA2


Item#:
sAP-1509
Size Price Quantity
100.0 ug $341.00
Catalog Number sAP-1509
Product Name Mouse Monoclonal Antibody to PRKAA2
Target Molecle PRKAA2
Aliases AMPK; AMPK2; PRKAA; AMPKa2
Species Human;Monkey;
MW 62.3kDa
Enterez GeneID 5563
General Information The protein encoded by this gene is a catalytic subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. Studies of the mouse counterpart suggest that this catalytic subunit may control whole-body insulin sensitivity and is necessary for maintaining myocardial energy homeostasis during ischemia.
Immunogen Purified recombinant fragment of human PRKAA2 (AA
Clone MM8E11H5
Isotype Mouse IgG1
Size and Concentration 100µg/1mg/ml
Supplied As Lyophilized Powder from 100µl of Purified antibody in PBS with 0.05% sodium azide
Reconstitution and Storage Reconstitued with 100µl sterile DI H2O, at stored at 4°C or -20°C for short or long term storage.
Applications ELISA
References 1.Gene. 2015 Aug 10;567(2)

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