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Mouse Monoclonal Antibody to Phospho-4E-BP1 (Ser65)

Size Price Quantity
50.0 ug $245.00
Catalog Number sAP-1505
Product Name Mouse Monoclonal Antibody to Phospho-4E-BP1 (Ser65)
Target Molecle Phospho-4E-BP1 (Ser65)
Aliases EIF4EBP1; BP-1; 4EBP1; 4E-BP1; PHAS-I
Species Human;
MW 12.6kDa
Enterez GeneID 1978
General Information This gene encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E), which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling, resulting in its dissociation from eIF4E and activation of mRNA translation.
Immunogen Synthesized peptide of human Phospho-4E-BP1 (Ser65).
Clone MM1E2E7
Isotype Mouse IgG1
Size and Concentration 100µg/1mg/ml
Supplied As Lyophilized Powder from 100µl of Purified antibody in PBS with 0.05% sodium azide
Reconstitution and Storage Reconstitued with 100µl sterile DI H2O, at stored at 4°C or -20°C for short or long term storage.
Applications ELISA
References 1.J Mol Biol. 2014 Oct 23;426(21)