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Mouse Monoclonal Antibody to CCND1


Item#:
sAP-1468
Size Price Quantity
100.0 ug $341.00
Catalog Number sAP-1468
Product Name Mouse Monoclonal Antibody to CCND1
Target Molecle CCND1
Aliases
Species Human;
MW 26kDa
Enterez GeneID 712
General Information The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance throughout the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK4 or CDK6, whose activity is required for cell cycle G1/S transition. This protein has been shown to interact with tumor suppressor protein Rb and the expression of this gene is regulated positively by Rb. Mutations, amplification and overexpression of this gene, which alters cell cycle progression, are observed frequently in a variety of tumors and may contribute to tumorigenesis.;
Immunogen Purified recombinant fragment of human CCND1 (AA
Clone MM3B6G3;
Isotype Mouse IgG1
Size and Concentration 100µg/1mg/ml
Supplied As Lyophilized Powder from 100µl of Purified antibody in PBS with 0.05% sodium azide
Reconstitution and Storage Reconstitued with 100µl sterile DI H2O, at stored at 4°C or -20°C for short or long term storage.
Applications ELISA
References 1.World J Gastroenterol. 2015 Jun 21;21(23)

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