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Mouse Monoclonal Antibody to DOC2


Item#:
sAP-1458
Size Price Quantity
100.0 ug $341.00
Catalog Number sAP-1458
Product Name Mouse Monoclonal Antibody to DOC2
Target Molecle DOC2
Aliases
Species Human;
MW 23.4kDa
Enterez GeneID 5899
General Information This gene encodes a mitogen-responsive phosphoprotein. It is expressed in normal ovarian epithelial cells, but is down-regulated or absent from ovarian carcinoma cell lines, suggesting its role as a tumor suppressor. This protein binds to the SH3 domains of GRB2, an adaptor protein that couples tyrosine kinase receptors to SOS (a guanine nucleotide exchange factor for Ras), via its C-terminal proline-rich sequences, and may thus modulate growth factor/Ras pathways by competing with SOS for binding to GRB2. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.;
Immunogen Purified recombinant fragment of human DOC2 (AA
Clone MM2H7C4;
Isotype Mouse IgG1
Size and Concentration 100µg/1mg/ml
Supplied As Lyophilized Powder from 100µl of Purified antibody in PBS with 0.05% sodium azide
Reconstitution and Storage Reconstitued with 100µl sterile DI H2O, at stored at 4°C or -20°C for short or long term storage.
Applications ELISA
References 1.Reprod Biol Endocrinol. 2015 Sep 4;13

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