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Mouse Monoclonal Antibody to PLCG1


Item#:
sAP-1454
Size Price Quantity
100.0 ug $341.00
Catalog Number sAP-1454
Product Name Mouse Monoclonal Antibody to PLCG1
Target Molecle PLCG1
Aliases PLC1; NCKAP3; PLC-II; PLC148; PLCgamma1
Species Human;
MW 148.5kDa
Enterez GeneID 5335
General Information The protein encoded by this gene catalyzes the formation of inositol 1,4,5-trisphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of receptor-mediated tyrosine kinase activators. For example, when activated by SRC, the encoded protein causes the Ras guanine nucleotide exchange factor RasGRP1 to translocate to the Golgi, where it activates Ras. Also, this protein has been shown to be a major substrate for heparin-binding growth factor 1 (acidic fibroblast growth factor)-activated tyrosine kinase. Two transcript variants encoding different isoforms have been found for this gene.;
Immunogen Purified recombinant fragment of human PLCG1 (AA
Clone MM2F3E10;
Isotype Mouse IgG2a
Size and Concentration 100µg/1mg/ml
Supplied As Lyophilized Powder from 100µl of Purified antibody in PBS with 0.05% sodium azide
Reconstitution and Storage Reconstitued with 100µl sterile DI H2O, at stored at 4°C or -20°C for short or long term storage.
Applications ELISA
References 1.Cancer Discov. 2014 Apr;4(4)

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