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Mouse Monoclonal Antibody to MET


Item#:
sAP-1430
Size Price Quantity
50.0 ug $245.00
100.0 ug $320.00
Catalog Number sAP-1430
Product Name Mouse Monoclonal Antibody to MET
Target Molecle MET
Aliases CIRP
Species Human;
MW 18.6kDa
Enterez GeneID 1153
General Information This gene encodes a member of the receptor tyrosine kinase family of proteins and the product of the proto-oncogene MET. The encoded preproprotein is proteolytically processed to generate alpha and beta subunits that are linked via disulfide bonds to form the mature receptor. Further processing of the beta subunit results in the formation of the M10 peptide, which has been shown to reduce lung fibrosis. Binding of its ligand, hepatocyte growth factor, induces dimerization and activation of the receptor, which plays a role in cellular survival, embryogenesis, and cellular migration and invasion. Mutations in this gene are associated with papillary renal cell carcinoma, hepatocellular carcinoma, and various head and neck cancers. Amplification and overexpression of this gene are also associated with multiple human cancers.;
Immunogen Purified recombinant fragment of human MET (AA
Clone MM5E9B7;
Isotype Mouse IgG2a
Size and Concentration 100µg/1mg/ml
Supplied As Lyophilized Powder from 100µl of Purified antibody in PBS with 0.05% sodium azide
Reconstitution and Storage Reconstitued with 100µl sterile DI H2O, at stored at 4°C or -20°C for short or long term storage.
Applications ELISA
References 1.Oncotarget. 2015 Jun 30;6(18)
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