Home Page > ANTIBODY > MONOCLONAL ANTIBODY > Mouse Monoclonal Antibody >  Mouse Monoclonal Antibody to MET

Mouse Monoclonal Antibody to MET


Item#:
sAP-1429
Size Price Quantity
50.0 ug $245.00
100.0 ug $320.00
Catalog Number sAP-1429
Product Name Mouse Monoclonal Antibody to MET
Target Molecle MET
Aliases E2-2; ITF2; PTHS; SEF2; FECD3; ITF-2; SEF-2; TCF-4
Species Human; Monkey;
MW 71.3kDa
Enterez GeneID 6925
General Information This gene encodes a member of the receptor tyrosine kinase family of proteins and the product of the proto-oncogene MET. The encoded preproprotein is proteolytically processed to generate alpha and beta subunits that are linked via disulfide bonds to form the mature receptor. Further processing of the beta subunit results in the formation of the M10 peptide, which has been shown to reduce lung fibrosis. Binding of its ligand, hepatocyte growth factor, induces dimerization and activation of the receptor, which plays a role in cellular survival, embryogenesis, and cellular migration and invasion. Mutations in this gene are associated with papillary renal cell carcinoma, hepatocellular carcinoma, and various head and neck cancers. Amplification and overexpression of this gene are also associated with multiple human cancers.;
Immunogen Purified recombinant fragment of human MET (AA
Clone MM5E9C4;
Isotype Mouse IgG1
Size and Concentration 100µg/1mg/ml
Supplied As Lyophilized Powder from 100µl of Purified antibody in PBS with 0.05% sodium azide
Reconstitution and Storage Reconstitued with 100µl sterile DI H2O, at stored at 4°C or -20°C for short or long term storage.
Applications ELISA
References 1.PLoS Biol. 2014 Dec 23;12(12)
N
N

ANGIO-PROTEOMIE, ALL RIGHTS RESERVED