Home Page > ANTIBODY > MONOCLONAL ANTIBODY > Mouse Monoclonal Antibody >  Mouse Monoclonal Antibody to BIN1

Mouse Monoclonal Antibody to BIN1


Item#:
sAP-1385
Size Price Quantity
50.0 ug $245.00
Catalog Number sAP-1385
Product Name Mouse Monoclonal Antibody to BIN1
Target Molecle BIN1
Aliases AMPH2; AMPHL; SH3P9
Species Human; Mouse;
MW 64.7kDa
Enterez GeneID 274
General Information This gene encodes several isoforms of a nucleocytoplasmic adaptor protein, one of which was initially identified as a MYC-interacting protein with features of a tumor suppressor. Isoforms that are expressed in the central nervous system may be involved in synaptic vesicle endocytosis and may interact with dynamin, synaptojanin, endophilin, and clathrin. Isoforms that are expressed in muscle and ubiquitously expressed isoforms localize to the cytoplasm and nucleus and activate a caspase-independent apoptotic process. Studies in mouse suggest that this gene plays an important role in cardiac muscle development. Alternate splicing of the gene results in several transcript variants encoding different isoforms. Aberrant splice variants expressed in tumor cell lines have also been described.;
Immunogen Purified recombinant fragment of human BIN1 (AA
Clone MM3B6A4;
Isotype Mouse IgG2b
Size and Concentration 100µg/1mg/ml
Supplied As Lyophilized Powder from 100µl of Purified antibody in PBS with 0.05% sodium azide
Reconstitution and Storage Reconstitued with 100µl sterile DI H2O, at stored at 4°C or -20°C for short or long term storage.
Applications ELISA
References 1.Oncogene. 2013 Apr 18;32(16)
N
N

ANGIO-PROTEOMIE, ALL RIGHTS RESERVED