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Mouse Monoclonal Antibody to UCP3


Item#:
sAP-1338
Size Price Quantity
50.0 ug $245.00
100.0 ug $320.00
Catalog Number sAP-1338
Product Name Mouse Monoclonal Antibody to UCP3
Target Molecle UCP3
Aliases SLC25A9
Species Human;
MW 34.2kDa
Enterez GeneID 7352
General Information Mitochondrial uncoupling proteins (UCP) are members of the larger family of mitochondrial anion carrier proteins (MACP). UCPs separate oxidative phosphorylation from ATP synthesis with energy dissipated as heat, also referred to as the mitochondrial proton leak. UCPs facilitate the transfer of anions from the inner to the outer mitochondrial membrane and the return transfer of protons from the outer to the inner mitochondrial membrane. They also reduce the mitochondrial membrane potential in mammalian cells. The different UCPs have tissue-specific expression; this gene is primarily expressed in skeletal muscle. This gene's protein product is postulated to protect mitochondria against lipid-induced oxidative stress. Expression levels of this gene increase when fatty acid supplies to mitochondria exceed their oxidation capacity and the protein enables the export of fatty acids from mitochondria. UCPs contain the three solcar protein domains typically found in MACPs. Two splice variants have been found for this gene.;
Immunogen Purified recombinant fragment of human UCP3 (AA
Clone MM6B8C6;
Isotype Mouse IgG2a
Size and Concentration 100µg/1mg/ml
Supplied As Lyophilized Powder from 100µl of Purified antibody in PBS with 0.05% sodium azide
Reconstitution and Storage Reconstitued with 100µl sterile DI H2O, at stored at 4°C or -20°C for short or long term storage.
Applications ELISA
References 1.BMC Cancer. 2013 Mar 14;13
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