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Mouse Monoclonal Antibody to RAD50


Item#:
sAP-1312
Size Price Quantity
50.0 ug $245.00
100.0 ug $320.00
Catalog Number sAP-1312
Product Name Mouse Monoclonal Antibody to RAD50
Target Molecle RAD50
Aliases NBSLD; RAD502; hRad50
Species Human; Rat;
MW 154kDa
Enterez GeneID 10111
General Information The protein encoded by this gene is highly similar to Saccharomyces cerevisiae Rad50, a protein involved in DNA double-strand break repair. This protein forms a complex with MRE11 and NBS1. The protein complex binds to DNA and displays numerous enzymatic activities that are required for nonhomologous joining of DNA ends. This protein, cooperating with its partners, is important for DNA double-strand break repair, cell cycle checkpoint activation, telomere maintenance, and meiotic recombination. Knockout studies of the mouse homolog suggest this gene is essential for cell growth and viability. Mutations in this gene are the cause of Nijmegen breakage syndrome-like disorder.;
Immunogen Purified recombinant fragment of human RAD50 (AA
Clone MM3D2G10;
Isotype Mouse IgG2a
Size and Concentration 100µg/1mg/ml
Supplied As Lyophilized Powder from 100µl of Purified antibody in PBS with 0.05% sodium azide
Reconstitution and Storage Reconstitued with 100µl sterile DI H2O, at stored at 4°C or -20°C for short or long term storage.
Applications ELISA
References 1.Breast Cancer Res Treat. 2010 Sep;123(2)
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