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Mouse Monoclonal Antibody to UCP2


Item#:
sAP-1295
Size Price Quantity
50.0 ug $245.00
100.0 ug $320.00
Catalog Number sAP-1295
Product Name Mouse Monoclonal Antibody to UCP2
Target Molecle UCP2
Aliases UCPH; BMIQ4; SLC25A8
Species Human;
MW 33.2kDa
Enterez GeneID 7351
General Information Mitochondrial uncoupling proteins (UCP) are members of the larger family of mitochondrial anion carrier proteins (MACP). UCPs separate oxidative phosphorylation from ATP synthesis with energy dissipated as heat, also referred to as the mitochondrial proton leak. UCPs facilitate the transfer of anions from the inner to the outer mitochondrial membrane and the return transfer of protons from the outer to the inner mitochondrial membrane. They also reduce the mitochondrial membrane potential in mammalian cells. Tissue specificity occurs for the different UCPs and the exact methods of how UCPs transfer H+/OH- are not known. UCPs contain the three homologous protein domains of MACPs. This gene is expressed in many tissues, with the greatest expression in skeletal muscle. It is thought to play a role in nonshivering thermogenesis, obesity and diabetes. Chromosomal order is 5'-UCP3-UCP2-3'.;
Immunogen Purified recombinant fragment of human UCP2 (AA
Clone MM6C8B3;
Isotype Mouse IgG1
Size and Concentration 100µg/1mg/ml
Supplied As Lyophilized Powder from 100µl of Purified antibody in PBS with 0.05% sodium azide
Reconstitution and Storage Reconstitued with 100µl sterile DI H2O, at stored at 4°C or -20°C for short or long term storage.
Applications ELISA
References 1.Neurosci Lett. 2014 Jan 24;559
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