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Mouse Monoclonal Antibody to KPNA2


Item#:
sAP-1284
Size Price Quantity
50.0 ug $245.00
100.0 ug $320.00
Catalog Number sAP-1284
Product Name Mouse Monoclonal Antibody to KPNA2
Target Molecle KPNA2
Aliases QIP2; RCH1; IPOA1; SRP1alpha
Species Human; Mouse;
MW 58kDa
Enterez GeneID 3838
General Information The import of proteins into the nucleus is a process that involves at least 2 steps. The first is an energy-independent docking of the protein to the nuclear envelope and the second is an energy-dependent translocation through the nuclear pore complex. Imported proteins require a nuclear localization sequence (NLS) which generally consists of a short region of basic amino acids or 2 such regions spaced about 10 amino acids apart. Proteins involved in the first step of nuclear import have been identified in different systems. These include the Xenopus protein importin and its yeast homolog, SRP1 (a suppressor of certain temperature-sensitive mutations of RNA polymerase I in Saccharomyces cerevisiae), which bind to the NLS. KPNA2 protein interacts with the NLSs of DNA helicase Q1 and SV40 T antigen and may be involved in the nuclear transport of proteins. KPNA2 also may play a role in V(D)J recombination. ;
Immunogen Purified recombinant fragment of human KPNA2 (AA
Clone MM1E8B7;
Isotype Mouse IgG1
Size and Concentration 100µg/1mg/ml
Supplied As Lyophilized Powder from 100µl of Purified antibody in PBS with 0.05% sodium azide
Reconstitution and Storage Reconstitued with 100µl sterile DI H2O, at stored at 4°C or -20°C for short or long term storage.
Applications ELISA
References 1.World J Gastroenterol. 2013 Apr 21;19(15)
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