Angio-Proteomie - Angio-Proteomie

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Angio-Proteomie, a globle supplier of biomedical research reagents, is

dedicated in serving the Biomedical Research Communities, with top quality

reagents, including antibodies, recombinant proteins, recombinant

adenoviruses, primary endothelial cells, and small interfering RNA products.

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Featured Products

ANTIBODIES

Functional antibodies

Agonistic antibodis: VEGFR1 and VEGFR2

Antagonistic antibodies: VEGFR1, VEGFR2, VEGFR3, PECAM1 (CD31) and endoglin (CD105)

Neutralizing antibodies: VEGF-A, VEGF-C, and PlGF

Mouse endothelial,inflammatory cells and CDs markers (IHC on paraffin sections)

Endothelial markers: CD31, CD34, VEGFR2, and CD105 et. al.

Mouse CDs markers: CD3, CD4, CD8, CD45R, Macrophage, Neutrophil, and Dentritic cell et. al.

Azide Free & Low Endotoxin Monoclonal Antibody for in vivo and in vitro functional studies

Rat anti mouse: CD3, CD4, CD8a, CD11a, CD11b, CD16/32, CD18, CD25, CD40, CD44, CD45RB, CD54 (ICAM1), CD62L (L-Selectin), CD70, CD86 (B7-2), CD103, CD106 (VCAM1), CD119 (INF gamma Receptor alpha chain), CD122 (IL-2R beta chain), CD127 (IL-7R alpha chain), CD134 (OX-40), CD252 (OX40 Ligand), CD275 (B7-RP1), LPAM-1 (Integrin alpha4-beta7), MAdCAM-1, IL-2, CD25 (IL-2R alpha), IL-4, IL-6, CD126 (IL-6R alpha chain), IL-10, CD210 (IL-10R), IL-12, Interferon gamma, TNF alpha, ICOS (CD278), Integrin beta-7, GITR, Thy-1.2, VLA-4 (CD49d), Gr-1 (Ly-6G), 33D1 (a dendritic cell marker), B7-H1 (PD-L1), TCR beta chain, CD205 (a dendritic cell marker), MHC class II, 4-1BBL (CDw137L), B7-DC (PD-L2, CD273) et al.

Hamster anti mouse: CD3e, CD11c, CD28, CD154 (CD40L), CD80 (B7-1), CD152 (CTLA-4), CD279 (PD-1), CD314 (NKG2D), TCR (delta/gamma), et al.

One step WB/IHC/ELISA antibodies for Tags and Internal loading control molecules

HRP-conjugated Anti-Tag molecules: AU1, Myc, His, HA, GST, and V5 et. al.

HRP-conjugated Anti-Internal Loading Control molecules: Beta-tubulin, beta-actin, and GAPDH

RECOMBINANT PROTEIN

Angiopoietin and Tie       VEGFs                             FGFs                    Soluble Receptors             PDGFs

BMPs                                  CSFs                               GROs                    IGFs                                     SCFs

Interferons                       Interleukins                   MCPs                  MIPs                                     SDFs

TNFs                                  Reliatech Products

PRIMARY CELLS

Human Primary Endothelial Cells:

Human Umbilical Vein Endothelial Cells, GFP Expressing Human Umbilical Vein Endothelial Cells, Human Brian Microvascular Endothelial Cells, GFP Expressing Human Brain Microvascular Endothelial Cells, Human Dermal Lymphatic Microvascular Endothelial Cells, Human Glomerular Microvascular Endothelial Cells, GFP Expressing Human Glomerular Microvascular Endothelial Cells, Human Dermal Microvascular Endothelial Cells, Human Aortic Artery Endothelial Cells, GFP Expressing Human Aortic Artery Endothelial Cells, Human Coronary Artery Endothelial Cells, GFP Expressing Human Coronary Artery Endothelial Cells.

Mouse Endothelial cells:

Mouse Aortic Endothelial Cells, GFP Expressing Mouse Aortic Endothelial Cells, Mouse Brian Microvascular Endothelial Cells, GFP Expressing Mouse Brian Microvascular Endothelial Cells.

shRNA stable transfected HUVECs:

Control shRNA Stable Trannsfected HUVECs, Human PECAM1 shRNA Stable Trannsfected HUVECs, Human VEGFR1 shRNA Stable Trannsfected HUVECs, Human VEGFR2 shRNA Stable Trannsfected HUVECs

PREMADE RECOMBINANT ADENOVIRUS

SMALL INTERFERING RNA (siRNA)

Products from Angio-Proteomie in the Literature

mV1007m-m (Mouse anti-mouse VEGF blocking antibody)

Fan Zhang, Zhongshu Tang, Xu Hou, Johan Lennartsson, Yang Li, Alexander W. Koch, Pierre Scotney, Chunsik Lee, Pachiappan Arjunan, Lijin Dong, Anil Kumar, Tuomas T. Rissanen, Bin Wang, Nobuo Nagai, Pierre Fons, Robert Fariss, Yongqing Zhang, Eric Wawrousek, Ginger Tansey, James Raber, Guo-Hua Fong, Hao Ding, David A. Greenberg, Kevin G. Becker, Jean-Marc Herbert, Andrew Nash, Seppo Yla-Herttuala, Yihai Cao, Ryan J. Watts, and Xuri Li. VEGF-B is dispensable for blood vessel growth but critical for their survival, and VEGF-B targeting inhibits pathological angiogenesis. PNAS 2009 106 (15) 6152-6157. http://www.pnas.org/content/suppl/2009/04/03/0813061106.DCSupplemental/0813061106SI.pdf

Xu Hou, Anil Kumar, Chunsik Lee, Bin Wang, Pachiappan Arjunan, Lijin Dong, Arvydas Maminishkis, Zhongshu Tang, Yang Li, Fan Zhang, Shi-Zhuang Zhang, Piotr Wardega, Sagarika Chakrabarty, Baoying Liu, Zhijian Wu, Peter Colosi, Robert N. Fariss, Johan Lennartsson, Robert Nussenblatt, J. Silvio Gutkind, Yihai Cao, and Xuri Li. PDGF-CC blockade inhibits pathological angiogenesis by acting on multiple cellular and molecular targets. PNAS 2010 107 (27) 12216-12221

http://www.pnas.org/content/suppl/2010/06/15/1004143107.DCSupplemental/pnas.201004143SI.pdf

mV1001.1r-m (rat anti–mouse VEGFR-2 antagonist antibody)

Wuest TR, Carr DJ. VEGF-A expression by HSV-1-infected cells drives corneal lymphangiogenesis. J Exp Med. 2010 Jan 18;207(1):101-15. http://jem.rupress.org/content/207/1/101.full.pdf+html

mV1004m-h (agonistic antibody, mouse anti human VEGFR1, monoclonal)

Malgorzata M. Ptaszynska, Michael L. Pendrak, Russell W. Bandle, Mary L. Stracke,* and David D. Roberts. Positive feedback between vascular endothelial growth factor-A and autotaxin in ovarian cancer cells. Mol Cancer Res. 2008 March; 6(3): 352–363.

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2442564/pdf/nihms53142.pdf

Ptaszynska MM, Pendrak ML, Stracke ML, Roberts DD. Autotaxin signaling via lysophosphatidic acid receptors contributes to vascular endothelial growth factor-induced endothelial cell migration. Mol Cancer Res. 2010 Mar;8(3):309-21. http://mcr.aacrjournals.org/content/8/3/309.abstract

mV1001.3m-h (agonistic antibody, mouse anti human VEGFR2, monoclonal)

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2442564/pdf/nihms53142.pdf

mV1001.1m-h (antagonistic antibody mouse anti human VEGFR2, monoclonal)

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2442564/pdf/nihms53142.pdf

pV1004R-h (antagonistic antibody rabbit anti human VEGFR1, polyclonal)

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2442564/pdf/nihms53142.pdf

pV1006R-r (Rabbit neutralizing antibody to VEGF-C, polyclonal)

Romulo J C Albuquerque, Takahiko Hayashi, Won Gil Cho, Mark E Kleinman, Sami Dridi, Atsunobu Takeda, Judit Z Baffi, Kiyoshi Yamada, Hiroki Kaneko, Martha G Green, Joe Chappell, Jörg Wilting, Herbert A Weich, Satoru Yamagami, Shiro Amano, Nobuhisa Mizuki, Jonathan S Alexander, Martha L Peterson, Rolf A Brekken, Masanori Hirashima, Seema Capoor, Tomohiko Usui, Balamurali K Ambati & Jayakrishna Ambati. Alternatively spliced vascular endothelial growth factor receptor-2 is an essential endogenous inhibitor of lymphatic vessel growth. Nature Medicine 15, 1023 - 1030 (2009) Published online: 9 August 2009, doi:10.1038/nm.2018

http://www.nature.com/nm/journal/v15/n9/pdf/nm.2018.pdf

mAP-0029 (rat anti mouse macrophage marker)

Ahmad H Bani-Hani, Jeffery A Leslie, Hiroshi Asanuma, Charles A Dinarello, Matthew T Campbell, Daniel R Meldrum, Honji Zhang, Karen Hile and Kirstan K Meldrum. IL-18 neutralization ameliorates obstruction-induced epithelial–mesenchymal transition and renal fibrosisIL-18 neutralization ameliorates renal fibrosis. Kidney International 76, 500-511 , 2009

http://www.nature.com/ki/journal/v76/n5/full/ki2009216a.html

mAP-0031 (rat anti mouse CD34)

Xue Y, Lim S, Bråkenhielm E, Cao Y. Adipose angiogenesis: quantitative methods to study microvessel growth, regression and remodeling in vivo. Nat Protoc. 2010;5(5):912-20.

http://www.nature.com/nprot/journal/v5/n5/abs/nprot.2010.46.html

mAP-0032 (rat anti mouse PECAM1, CD31)

Angst E, Chen M, Mojadidi M, Hines OJ, Reber HA, Eibl G. Bioluminescence Imaging of Angiogenesis in a Murine Orthotopic Pancreatic Cancer Model. Mol Imaging Biol. 2010 Apr 8. [Epub ahead of print]

http://www.springerlink.com/content/p01u703245304046/fulltext.pdf

mAP-0035 (rat anti mouse CD4, monoclonal)

Mohammed J, Ryscavage A, Perez-Lorenzo R, Gunderson AJ, Blazanin N, Glick AB. TGFbeta1-Induced Inflammation in Premalignant Epidermal Squamous Lesions Requires IL-17. J Invest Dermatol. 2010 Apr 22.

http://www.nature.com/jid/journal/vaop/ncurrent/abs/jid201092a.html

mAP-0036 (rat anti mouse CD8a)

http://www.nature.com/jid/journal/vaop/ncurrent/abs/jid201092a.html

cAP-0004: Human glomerular microvascular endothelial cells

Jian-Wei Gu, R. Davis Manning, Jr., Emily Young, Megan Shparago, Brandi Sartin, and Amelia Purser Bailey. Vascular endothelial growth factor receptor inhibitor enhances dietary salt-induced hypertension in Sprague-Dawley rats. Am J Physiol Regul Integr Comp Physiol 297: R142–R148, 2009. http://ajpregu.physiology.org/cgi/reprint/297/1/R142.pdf

cAP-0002: Human brain microvascular endothelial cells

Akers SM, O'Leary HA, Minnear FL, Craig MD, Vos JA, Coad JE, Gibson LF. VE-cadherin and PECAM-1 enhance ALL migration across brain microvascular endothelial cell monolayers. Exp Hematol. 2010 May 12. http://www.ncbi.nlm.nih.gov/pubmed/20470859

rAP-0015 Recombinant orf virus VEGF-E

Mary A. GRUMMER, Jeremy A. SULLIVAN, Ronald R. MAGNESS and Ian M. BIRD. Vascular endothelial growth factor acts through novel, pregnancy-enhanced receptor signalling pathways to stimulate endothelial nitric oxide synthase activity in uterine artery endothelial cells. Biochem. J. (2009) 417, 501–511. http://www.biochemj.org/bj/417/0501/4170501.pdf